Dan Grupe, PhD

Center for Healthy Minds
625 West Washington Ave.
Madison, WI 53703

I'm an Assistant Scientist in the Center for Healthy Minds and the Waisman Laboratory for Brain Imaging and Behavior at the University of Wisconsin-Madison.

I study the brain mechanisms by which humans can adaptively prepare for future events in anticipation of their actual occurrence, particularly when faced with uncertainty about the future. I have studied how these adaptive anticipatory processes break down and contribute to the development of anxiety disorders. I have used a variety of tools in this work, including functional magnetic resonance imaging, peripheral psychophysiological methods, and behavioral and self-report measures, to paint a complete picture of individual differences in affective processing and the brain, both in healthy individuals and in clinical populations.

I am also deeply interested in the breadth of individual responses to stressful and traumatic life events, and the relationship between subjective perceptions of stress and the development of PTSD and other stress-related disorders. In ongoing research, I am investigating the psychological and neurobiological factors that allow some individuals to thrive in the face of stressful life events, and investigating the potential of mindfulness-based interventions to enhance these factors and promote more resilient responses in high-stress individuals, such as law enforcement and military populations.